Molecular Diagnostics Made SimpleGenie ® HT was developed specifically for high-throughput environments offering diagnostic testing based on isothermal amplification methods. As with the smaller Genie ® instruments, the Genie ® HT can be fully controlled from its embedded touchscreen and also uses the custom 8-microtube Genie ® Strip. This system was designed to be modular and can be procured with any number of sample blocks installed up to a maximum of 12. Instruments delivered with less than 12 blocks may be upgraded at any time. The Genie ® HT offers full random access with any blocks used at any time.
OptiGene Limited was formed in 2008 to develop and deliver advanced molecular diagnostics solutions for applications across a range of market sectors. The company is privately owned and is based in Horsham in the South of England, close to Gatwick Airport and within an hour of Heathrow Airport and the centre of London. OptiGene was established with the primary goal of providing the highest quality instrumentation and performance-leading reagents to support isothermal amplification of DNA and RNA. The market pull for this venture came from the growing demands around the world for field testing, rapid results and point-of-care diagnostics.
OptiGene has developed innovative products that support sensitive and specific detection of bacteria and viruses for use in the fields of plant health, food safety, veterinary medicine, environmental monitoring and healthcare. Bio-defence and forensics are also key markets that OptiGene addresses, either directly or through its growing network of international distributors. The company has exploited its expertise in both instrument design and enzymology to develop a sophisticated open platform that will support all isothermal amplification methods. Ultra-sensitive molecular detection that has been constrained to laboratory use by highly-qualified personnel and taking hours to complete can now be deployed to point of application and run with very little training, producing results in single minutes.
The Genie II instrument is the flagship product of OptiGene and has been in full production since the spring of 2011. Genie II is now found in a variety of diagnostic settings around the world. It is supported by specially-designed plastic strips that have lockable caps and that are easy to handle. Enzymes are available in the form of several master mixes that feature combinations of high-speed operation, inherent RT activity and thermostability. A continuous programme of development is maintained at OptiGene in order to satisfy the evolving demands of its customers and the wider market. New instruments are planned that will include a smaller device that will suit on-site use and more sophisticated optical arrangements that can support multiplexed assays. Improvements in the company’s enzymes are on-going with faster and more stable master mixes planned for release. OptiGene can also offer to develop variants of its products on behalf of OEM customers and these can adopt the customer’s corporate branding and include special features.
OptiGene Limited declares that, to the best of our knowledge, all electrical and electronic equipment (EEE) sold by the company are in compliance with Directive 2011/65/EU of the European Parliament and of the Council of 8 June 2011 on the restriction of the use of certain hazardous substances in electrical and electronic equipment (also known as “RoHS2”).
OptiGene Limited also declares that no products sold by the company are known to contain any of the substances of very high concern (SVHC) as intentionally added components with regards to the European Regulation No. 1907/2006 (Registration, Evaluation, Authorisation & restriction of Chemicals).
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